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pCI-Caspase 1 Citations (7)

Originally described in: AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA Nature. 2009 Mar 26. 458(7237):514-8.
PubMed Journal

Articles Citing pCI-Caspase 1

Articles
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation. Zhong FL, Mamai O, Sborgi L, Boussofara L, Hopkins R, Robinson K, Szeverenyi I, Takeichi T, Balaji R, Lau A, Tye H, Roy K, Bonnard C, Ahl PJ, Jones LA, Baker P, Lacina L, Otsuka A, Fournie PR, Malecaze F, Lane EB, Akiyama M, Kabashima K, Connolly JE, Masters SL, Soler VJ, Omar SS, McGrath JA, Nedelcu R, Gribaa M, Denguezli M, Saad A, Hiller S, Reversade B. Cell. 2016 Sep 22;167(1):187-202.e17. doi: 10.1016/j.cell.2016.09.001. PubMed
Caspase-1 regulates cellular trafficking via cleavage of the Rab7 adaptor protein RILP. Adams A, Weinman SA, Wozniak AL. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2619-2624. doi: 10.1016/j.bbrc.2018.08.013. Epub 2018 Aug 9. PubMed
Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes. Mambwe B, Neo K, Javanmard Khameneh H, Leong KWK, Colantuoni M, Vacca M, Muimo R, Mortellaro A. Front Immunol. 2019 Jul 5;10:1556. doi: 10.3389/fimmu.2019.01556. eCollection 2019. PubMed
Complementary regulation of caspase-1 and IL-1beta reveals additional mechanisms of dampened inflammation in bats. Goh G, Ahn M, Zhu F, Lee LB, Luo D, Irving AT, Wang LF. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28939-28949. doi: 10.1073/pnas.2003352117. Epub 2020 Oct 26. PubMed
SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis. Shen S, Guo H, Li Y, Zhang L, Tang Y, Li H, Li X, Wang P-H, Yu X-F, Wei W. J Virol. 2024 Feb 20;98(2):e0190923. doi: 10.1128/jvi.01909-23. Epub 2024 Jan 30. PubMed
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Damianou A, Liang Z, Lassen F, Vendrell I, Vere G, Hester S, Charles PD, Pinto-Fernandez A, Santos A, Fischer R, Kessler BM. Life Sci Alliance. 2024 Mar 7;7(5):e202302245. doi: 10.26508/lsa.202302245. Print 2024 May. PubMed
A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis. Asare Y, Yan G, Schlegl C, Prestel M, van der Vorst EPC, Teunissen AJP, Aronova A, Tosato F, Naser N, Caputo J, Prevot G, Azzun A, Wefers B, Wurst W, Schneider M, Forne I, Bidzhekov K, Naumann R, van der Laan SW, Brandhofer M, Cao J, Roth S, Malik R, Tiedt S, Mulder WJM, Imhof A, Liesz A, Weber C, Bernhagen J, Dichgans M. Immunity. 2025 Mar 11;58(3):555-567.e9. doi: 10.1016/j.immuni.2025.01.003. Epub 2025 Jan 28. PubMed

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